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Life
Science: Why are My Eyes Brown? Introduction: In 1868, Gregor Mendel published some experiments he performed with pea plants. In this work, he discovered the principles of heredity. He spent 8 years following what happened to various traits of pea plants such as pea shape as he crossed different varieties of plants. He meticulously followed each generation and recorded the crosses he made and the traits of the offspring. From this he was able to conclude: 2 genes control each trait in a hybrid (Law of Segregation), and in a Mendelian hybrid, one of the two genes controlling the given trait will be dominant. Only the dominant trait will be expressed. This second observation is now called the Law of Dominance. Teachers Notes: Download: (Abobe Acrobat Reader required--download free reader) Print the "Why are My Eyes Brown?" activity. Print the Mendelian Traits in Humans" woorksheets. In humans, one allele is inherited from ones biological father and one allele from ones biological mother for each genetic trait. This pair of alleles can be dominant, recessive, or hybrid. The dominant and recessive conditions are called pure or homozygous since both genes present are identical. The hybrid condition possesses one of each gene type, and is called heterozygous. The genetic structure is called the genotype. Although the genotype of an individual may differ from another's, their outward appearance for a particular trait may be identical. The outward appearance is called the phenotype. Take for example someone who inherits R (can roll tongue) from their mother and r (cannot roll tongue) from their father. Their genotype is Rr. Another individual inherits an R from both their mother and father. This individuals genotype is RR. Since the ability to roll your tongue is dominant, both the Rr and RR individuals will be able to roll their tongues. Hence, their phenotype is R. The laws of inheritance are inherently the laws of chance. In a hybrid x cross, (the case where the mother and father are both heterozygous for a given trait), every offspring has a 50:50 chance of inheriting the dominant or recessive gene. A common way of illustrating this is with a Punnett Square:
The offspring in this example have a 50% change of being heterozygous for the X trait and 25% chance of being homozygous for the recessive x and 25% chance of 25% of being homozygous for the dominant X. Notice that the offspring have a 75% change of having the X phenotype. Note all traits are simple Mendelian types. Many traits demonstrate incomplete dominance, where no gene is expressed over the others. Traits will be blended together to form an intermediate trait. An example of this is hair color. The combination of a brown-haired gene and a blonde gene will most likely produce light brown hair. Other traits, such as skin color, are determined by multiple genes. One special form of linkage affects inheritance in a very visible fashion. Certain genes are located on the chromosomes that determine sex. Traits that do, such as color-blindness, appear primarily in males. Hemophilia is another example. In each of these sex-linked traits, the recessive gene is carried on the X chromosome. A female is XX and a male is genetically XY. Thus, a male only has one X chromosome and if it carries a gene for color blindness or hemophilia, then he will exhibit that trait. However, for a female, there is a second X chromosome. For her to exhibit such a trait there must be the much rarer occurrence of the recessive gene present on both chromosomes. Demonstration: Inheritance
of dominant and recessive traits. Lesson #3: Dominant Traits |
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